Straight up is a bartending term referring to a chilled drink served in a stemmed glass without ice.

Straight Up may also refer to:

Straight Up (book), by author, blogger, physicist and climate expert Joseph J. Romm

Straight Up (Harold Vick album), 1967

Straight Up (Badfinger album), 1971

Straight Up (Eric Alexander album), 1992

Straight Up (Bob James album), 1996

Straight Up (Jimmy McGriff album), 1998

"Straight Up" (Paula Abdul song), 1988

"Straight Up" (Chanté Moore song), 2000

Straight Up (TV series), a Canadian television series

Straight Up (1988 film), an anti-drug film

Straight Up (2019 film), an independent film by James Sweeney

The Straight Up, a documentary style of photography pioneered by Terry Jones