Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae
scientific article
Instance of
Subject
Aspergillus fumigatus
Aspergillus niger
MFS monocarboxylate transporter, putative
monocarboxylate transporter, putative
short chain dehydrogenase atsC, putative
putative oxidoreductase, 2OG-Fe(II) oxygenase family protein
fumigermin synthase
fungal Zn(2)-Cys(6) binuclear cluster domain protein
oxidoreductase, putative
aldose 1-epimerase family protein, putative
cytochrome P450 oxidoreductase, putative
zinc binding enoyl reductase, putative
fusarielin-like polyketide synthase, putative
Sterol regulatory element binding protein (SREBP)
Has domain(s) with predicted oxidoreductase activity and role in oxidation-reduction process
Has domain(s) with predicted NAD binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor activity and role in oxidation-reduction process
Putative polyketide synthase (PKS), encoded in a predicted secondary metabolite gene cluster
Ortholog of A. niger CBS 513.88 : An03g05130, Neosartorya fischeri NRRL 181 : NFIA_033600, Aspergillus wentii : Aspwe1_0307772 and Aspergillus versicolor : Aspve1_0036298
Ortholog of A. nidulans FGSC A4 : AN10993, A. niger CBS 513.88 : An03g05110, A. oryzae RIB40 : AO090701000405, Neosartorya fischeri NRRL 181 : NFIA_033610 and Aspergillus wentii : Aspwe1_0173185
Has domain(s) with predicted cation-transporting ATPase activity, metal ion binding, nucleotide binding activity, role in cation transport and integral component of membrane localization
Ortholog of A. nidulans FGSC A4 : AN7665, A. niger CBS 513.88 : An03g05100, Aspergillus wentii : Aspwe1_0113700, Aspergillus sydowii : Aspsy1_0090349 and Aspergillus terreus NIH2624 : ATET_08162
Ortholog of Aspergillus fumigatus A1163 : AFUB_018420
Ortholog(s) have NAD+ kinase activity, NADH kinase activity, role in NADP biosynthetic process, cellular iron ion homeostasis and cytoplasm, nucleus localization
Ortholog(s) have methionine-R-sulfoxide reductase activity, role in cellular response to oxidative stress and cytoplasm, nucleus localization
Ortholog of A. niger CBS 513.88 : An03g05060, A. oryzae RIB40 : AO090701000423, Aspergillus wentii : Aspwe1_0543025 and Aspergillus sydowii : Aspsy1_0077314
Ortholog(s) have cytosol, nucleus localization
Ortholog(s) have trans-aconitate 3-methyltransferase activity and cytosol localization
Has domain(s) with predicted oxidoreductase activity and role in metabolic process
Ortholog of A. oryzae RIB40 : AO090701000824, Neosartorya fischeri NRRL 181 : NFIA_033720, Aspergillus wentii : Aspwe1_0041628 and Aspergillus versicolor : Aspve1_0090015
Ortholog of A. oryzae RIB40 : AO090124000005, Aspergillus flavus NRRL 3357 : AFL2T_08039, Neosartorya fischeri NRRL 181 : NFIA_003660 and Aspergillus wentii : Aspwe1_0048316
Has domain(s) with predicted ATP binding, protein kinase activity, protein tyrosine kinase activity and role in protein phosphorylation
Has domain(s) with predicted carbon-nitrogen ligase activity, with glutamine as amido-N-donor activity
Has domain(s) with predicted RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity, role in regulation of transcription, DNA-templated and nucleus localization
Putative protein kinase
Has domain(s) with predicted role in transmembrane transport and integral component of membrane localization
Protein similar to polyketide synthases (PKS-like), encoded in a predicted secondary metabolite gene cluster
Ortholog of A. nidulans FGSC A4 : AN9006, A. fumigatus Af293 : Afu6g11710, Afu7g08440, Afu5g00145, A. niger CBS 513.88 : An09g05330 and A. oryzae RIB40 : AO090038000212
protein of unknown function
protein of unknown function
Putative polyketide synthase (PKS), encoded in a predicted secondary metabolite gene cluster
Has domain(s) with predicted oxidoreductase activity and role in metabolic process
Has domain(s) with predicted RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity, role in regulation of transcription, DNA-templated and nucleus localization
protein of unknown function
Has domain(s) with predicted role in transmembrane transport and integral component of membrane localization
Has domain(s) with predicted FAD binding, oxidoreductase activity and role in metabolic process
protein of unknown function
Ortholog of A. fumigatus Af293 : Afu2g17970/fgaFS, Aspergillus glaucus : Aspgl1_0180863, Neosartorya fischeri NRRL 181 : NFIA_095230 and Aspergillus fumigatus A1163 : AFUB_033660
Has domain(s) with predicted DNA binding, chromatin binding activity
Protein similar to nonribosomal peptide synthases (NRPS-like), encoded in a predicted secondary metabolite gene cluster
Has domain(s) with predicted RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity, role in regulation of transcription, DNA-templated and nucleus localization