Californication may refer to:

Californication (word), an expression that refers to the influx of Californians into various western states in the U.S.

Californication (album), a 1999 album by the Red Hot Chili Peppers

"Californication" (song), the title track and a single from the album

Californication Tour, worldwide concert tour following the album release

Californication (TV series), an American television series