Inflammasome

? TBD

Cytosolic multiprotein complex that mediates the activation of Caspase 1

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P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1.

scientific article published on April 2009

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

scientific article (publication date: 15 July 2009)

Extent of Ischemic Brain Injury After Thrombotic Stroke Is Independent of the NLRP3 (NACHT, LRR and PYD Domains-Containing Protein 3) Inflammasome

scientific article published on 01 May 2019

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

scientific article

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Wikipedia

Inflammasomes are cytosolic multiprotein complexes of the innate immune system responsible for the activation of inflammatory responses and cell death. They are formed as a result of specific cytosolic pattern recognition receptors (PRRs) sensing microbe-derived pathogen-associated molecular patterns (PAMPs), damage-associated molecular patterns...

Instance of

Cellular component

Subclass of

protein-containing complex

Protein complex

Wikidata

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