17th-century conjecture proved by Andrew Wiles in 1994
In number theory, Fermat's Last Theorem (sometimes called Fermat's conjecture, especially in older texts) states that no three positive integers a, b, and c satisfy the equation an + bn = cn for any integer value of n greater than 2. The cases n = 1 and n = 2 have been known since antiquity to have infinitely many solutions.