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Leukemia
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Blood cancers forming in the bone marrow
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Acute myeloid leukemia with translocation t(8;16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis
scientific article published on 24 October 2012
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
scientific article (publication date: 14 December 2010)
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia
scientific article
BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein
scientific article
Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia
scientific article
Recurring mutations found by sequencing an acute myeloid leukemia genome
scientific article
Evidence for Unusual Stability of ADP-Ribosyl Linkage to Membrane Proteins of a Murine Leukemic Cell Line
scientific article published on April 1, 1993
Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: by the GIMEMA Working Party on Chronic Myeloid Leukemia
article by Simona Soverini et al published 15 December 2006 in Clinical Cancer Research
Frontline imatinib treatment of chronic myeloid leukemia: no impact of age on outcome, a survey by the GIMEMA CML Working Party
article by Gabriele Gugliotta et al published 26 May 2011 in Blood
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
scientific article (publication date: 30 October 2009)
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Leukemia (also spelled leukaemia; pronounced loo-KEE-mee-É™) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called blasts or leukemia cells. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased...

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