protein sumoylation
process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein
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p14ARF interacts with the SUMO-conjugating enzyme Ubc9 and promotes the sumoylation of its binding partners.
Sumoylation of the net inhibitory domain (NID) is stimulated by PIAS1 and has a negative effect on the transcriptional activity of Net.