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Toll-like receptor
? TBD
Class of immune system proteins
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Toll-like receptor 2
Cell surface receptor found in humans
Subject of 20
The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.
scientific article
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
scientific article (publication date: May 2010)
Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly
scientific article published on November 2012
Recognition of Toxoplasma gondii by TLR11 prevents parasite-induced immunopathology
scientific journal article
Toll-like receptors in the CNS: implications for neurodegeneration and repair
scientific article published on January 2009
TLR-independent neutrophil-derived IFN-γ is important for host resistance to intracellular pathogens
scientific article published on 10 June 2013
TLR9 and IL-1R1 Promote Mobilization of Pulmonary Dendritic Cells during Beryllium Sensitization
scientific article published on 05 September 2018
An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4.
scientific article
Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity
scientific article
LPS/TLR4 signal transduction pathway
scientific article
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Wikipedia

Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single-spanning receptors usually expressed on sentinel cells such as macrophages and dendritic cells, that recognize structurally conserved molecules derived from microbes. Once these microbes have reached physical barriers such as the...

Instance of
group or class of proteins
Subclass of
Protein
Pattern recognition receptor
References
Wikidata