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Mutation
? TBD
Alteration in the nucleotide sequence of a genome
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Facets
2
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Genome instability
High frequency of mutations within the genome of a cellular lineage
Mutational signatures
characteristic combination of mutation types arising from a specific mutagenesis process
Instances
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whole genome duplication
duplication of an organism's genome
BRCA mutation
Medical condition
Subclasses
7
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Somatic mutation
Type of mutation on somatic cell
Neutral mutation
Changes to DNA with no overall impact
Gene duplication
Duplication of a gene sequence within a genome
Point mutation
Replacement, insertion, or deletion of a single DNA or RNA nucleotide
beneficial mutation
mutation that enhances fitness
Germline mutation
Inherited genetic variation
gene loss
set of processes resulting in the loss of an ancestral gene in a descendant population
Subject of
3
Invited review: Frontotemporal dementia caused by microtubule‐associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging
scientific article published on February 1, 2015
Is there a causal relationship between genetic changes and radiomics-based image features? An in vivo preclinical experiment with doxycycline inducible GADD34 tumor cells
scientific article published on 07 July 2015
Overview of non-coding mutations in chronic lymphocytic leukemia
scholarly article by Valeria Spina & Davide Rossi published 1 January 2019 in Molecular Oncology
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In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet...

Subclass of
Biological process
sequence variant
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