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Amyloidosis
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Metabolic disease involving abnormal deposited amyloid proteins
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Wikipedia

Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs and symptoms associated with amyloidosis. These include fatigue, peripheral edema, weight loss, shortness of breath, palpitations, and feeling faint with standing.

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Pathogenesis
References
Wikidata