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Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
Chemosensitivity linked to p73 function
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells
Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development