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molecular function
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dopamine binding
Y
100%
Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.
cocaine binding
N
0%
Interacting selectively and non-covalently with cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis.
G protein-coupled amine receptor activity
N
0%
Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
amorpha-4,11-diene 12-monooxygenase activity
?
TBD
Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]
voltage-gated potassium channel activity
?
TBD
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
voltage-gated cation channel activity
?
TBD
Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
potassium channel activity
?
TBD
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
voltage-gated chloride channel activity
?
TBD
Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
voltage-gated anion channel activity
?
TBD
Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
chloride channel activity
?
TBD
Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
voltage-gated ion channel activity
?
TBD
Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state i
voltage-gated channel activity
?
TBD
Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
ion transmembrane transporter activity
?
TBD
Enables the transfer of an ion from one side of a membrane to the other.
voltage-gated calcium channel activity
?
TBD
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
calcium channel activity
?
TBD
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
ATPase-coupled ion transmembrane transporter activity
?
TBD
Catalysis of the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate.
ATPase-coupled transmembrane transporter activity
?
TBD
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential
?
TBD
Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential.
ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential
?
TBD
Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.
identical protein binding
?
TBD
Interacting selectively and non-covalently with an identical protein or proteins.
voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential
?
TBD
Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
norepinephrine:sodium symporter activity
?
TBD
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) = norepinephrine(in) + Na+(in).
organic hydroxy compound transmembrane transporter activity
?
TBD
Enables the transfer of organic hydroxy compound from one side of the membrane to the other.
monoamine transmembrane transporter activity
?
TBD
Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of the membrane to the other.
organic cation transmembrane transporter activity
?
TBD
Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.
sodium:chloride symporter activity
?
TBD
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in).
voltage-gated ion channel activity involved in regulation of presynaptic membrane potential
?
TBD
Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse.
cholesterol O-acyltransferase activity
?
TBD
Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.
Catalysis
?
TBD
Process of increasing the rate of a chemical reaction
DNA (cytosine-5-)-methyltransferase activity
?
TBD
Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
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