Margaret A. Phillips · American biologist · YYNN

Margaret A. Phillips

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American biologist

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Works
12

Chemical genetics of Plasmodium falciparum

scientific article (publication date: 20 May 2010)

Structural Plasticity of Malaria Dihydroorotate Dehydrogenase Allows Selective Binding of Diverse Chemical Scaffolds

scientific article

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

scientific article published on 20 April 2021

Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice

scientific article published on April 2009

Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif

scientific article

Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum.

scientific article published on 04 June 2008

Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)

scientific article published on 30 June 2015

Analysis of flavin oxidation and electron-transfer inhibition in Plasmodium falciparum dihydroorotate dehydrogenase

scientific article

High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase

scientific article

Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies

scientific article

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Margaret A. Phillips (born November 3, 1959) is an American biologist who is the Sam G. Winstead and F. Andrew Bell Distinguished Chair in Biochemistry at the University of Texas Southwestern Medical Center. She was elected a Fellow of the National Academy of Sciences in 2021.

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National Academy of Sciences

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