Searching map area
Lissencephaly
? TBD
Birth defect in which the brain lacks surface folds
Join to rate
Ratings
0
Nobody has rated this yet. Be the first!
Subclasses
3
Influences rating
cobblestone lissencephaly
smooth pebbled appearance of the cerebral cortex with a thickened cortex and reduced and abnormal white matter
Norman–Roberts syndrome
Medical condition
Microlissencephaly
Microcephaly combined with lissencephaly
Subject of
4
Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3
scientific article
Reelin and Lissencephaly
Reelin mutations in mouse and man: from reeler mouse to schizophrenia, mood disorders, autism and lissencephaly
scientific article
Inhibition of histone deacetylases in rats self-administering cocaine regulates lissencephaly gene-1 and reelin gene expression, as revealed by microarray technique.
scientific article published on 2 February 2010
Lists
0
Join to rate

Lissencephaly (, meaning 'smooth brain') is a set of rare brain disorders whereby the whole or parts of the surface of the brain are smooth. It is caused by defective neuronal migration during the 12th to 24th weeks of gestation, resulting in a lack of development of brain folds (gyri) and grooves (sulci). It is a form of cephalic disorder....

Instance of
developmental defect during embryogenesis
designated intractable/rare disease
Rare disease
class of disease
Signs and symptoms
Subclass of
rare genetic developmental defect during embryogenesis
genetic syndromic intellectual disability
Disease
Wikidata